2025 POSTER PRESENTATIONS

POSTER SESSION A: Tuesday – Wednesday morning

A01: Cell Line Development Inefficiencies and Streamlining the Clone Selection Process for Protein Biologic Production with the Solentim® Ecosystem, Presented by Sivane K., Advanced Instruments LLC

A02: Design of Experiment (DoE) Enabled Scale-Up of Adeno-Associated Virus (AAV) Production, Presented by Mark W., APC Ltd.

A03: Exploring the Potential of Chromatography Resins in Therapeutic Treatment Delivery, Presented by David A., Bio-Rad Laboratories

A04: Scalable Purification with Prepacked Ceramic Hydroxyapatite Process-Scale Chromatography Columns, Presented by Franklin B., Bio-Rad Laboratories

A05: Separation of Bispecific-Antibody Related Impurities with Mixed-Mode Chromatography, Presented by Artur S., Bio-Rad Laboratories

A06: Optimising Poloxamer 188 for CHO and HEK Suspension Cells for Reduced Batch-to-Batch Variation, Presented by Geoff P., Croda International Plc

A07: Cas-CLOVER-Mediated Knockout of STAT1: A Novel Approach to Engineer Packaging HEK293 Cell Lines Used for rAAV Production, Presented by Charlie H., Demeetra Biotech

A08: Accelerating Development and Formulation Design of Biologics with Bayesian Optimisation, Presented by Isabel W., ETH Zurich

A09: How Bioreactor CFD Modeling Supports Scale Alignment in Technology Transfer, Presented by Clara D., Fresenius Kabi SwissBioSim GmbH

A10: A ‘Predict-First’ Approach - In Silico Strategies Can Enhance Efficiency in Monoclonal Antibody Bioprocess Development, Presented by Arghya B., FUJIFILM Diosynth Biotechnologies

A11: Development and Validation Of a ddPCR-Based Assay for Vector Copy Number (VCN), Presented by Jangeun C., GC Cell

A12: Integrated Analysis of Assays Drives Early Developability Assessment of Antibodies, Presented by Alexandre P., Genedata AG

A13: Building a Fully Single-Use Process: High Productivity Protein A Membrane Devices that Complement Disposable Upstream Technology, Presented by Jeff C., W.L. Gore & Associates, Inc.

A14: Biologic Stability: From CHO Cell Line Development to Late-Stage Stability Subvisible Particle Characterization, Presented by Paul D., Halo Labs

A15: Accelerated Lead Cell Line Selection Through Early Process and CQA Screening with Cutting-Edge Technologies, Presented by Amélie M., KBI Biopharma

A16: Development of an Intensified Plasmid Production Process based on Continuous Lysis and Membrane Chromatography, Presented by Philip G., Levitronix GmbH

A17: Real-Time Concentration Prediction of Proteins, LNPs, and Cells Using Temperature- and Viscosity-Based Regression Modeling, Presented by Antony S., Levitronix GmbH

A18: CHOZN® GS-/- Produces High Titer and High-Quality Bispecific Antibodies, Presented by Wilson F., Merck KGaA

A19: Intensifying DSP: Exploring Hybrid Depth Filters to Boost Purification Process Productivity, Presented by Katja G., Novartis Pharmaceutical Manufacturing GmbH

A20: Boost Bioprocess Development: Real-Time Cell Monitoring with Online Flow Cytometry, Presented by Marisa S., onCyt Microbiology AG

A21: Anti-Pan AAV – New Versatile Antibody for the Detection of Various AAV Serotypes Including Novel Capsids, Presented by Martin M., PROGEN Biotechnik GmbH

A22: Novel Culture Media for Inducing Erythroid Cells Differentiation, Presented by Kaapjoo P., RedGene, Inc.

A23: Dissolvable Microcarriers for Adherent Cell Culturing, Presented by Jos O., Rousselot Biomedical

A24: Lab-Scale Tools for Advanced LV Downstream Processing, Presented by Jennifer L., Sartorius Lab Instruments GmbH & Co. KG

A25: Transcriptomic Insights into mAb Producing CHO Cells, Presented by Merle R., Sartorius Stedim Cellca GmbH

A26: Rapid On-Line Analysis of Limiting Amino Acids Using the Advanced Auto-Sampling System Numera® and the Lucullus® Software, Presented by Boris H., SecureCell AG

A27: New Bioprocess Strategy with Fiber Chromatographic Clarification Platform from Discovery to Manufacturing, Presented by Masayuki N., Solventum

A28: Purification of a Recombinant Nanobody-Fc Fusion for SFTS Treatment Using Efficient Sequential Chromatography, Presented by Alessandra B., Sunresin New Materials Co., Ltd.

A29: Synthetic Genetic Elements for Improving Recombinant Protein Expression, Presented by Andy R., SynGenSys Ltd.

A30: Improving Time to Result: Leveraging Rapid Mycoplasma Detection and Sterility Testing in Cell Therapy Manufacturing, Presented by Lea J., Thermo Fisher Scientific

A31: Innovative Capture Purification Solutions for Therapeutic Antibody Manufacturing, Presented by Manuel M., Thermo Fisher Scientific

A32: Multi-Column Chromatography Platform for Monoclonal Antibody Results in High Purity and Effective Viral Clearance, Presented by Sebastian T., Tosoh Bioscience

A33: Implementation of Membrane Chromatography Technology in Downstream Process at 2kL Scale, Presented by Romain N., UCB Pharma S.A.

A34: Enhancing the Upstream Performance of Adeno-Associated Virus (AAV) Vector Manufacturing via Multivariate Data Analysis, Presented by Jens K., Viralgen Vector Core

A35: Establishment and Characterization of a Stable Producer Cell Line Generation Platform for the Manufacturing of Clinical-Grade Lentiviral Vectors, Presented by Ana AB., VIVEbiotech

A36: Speeding-Up Process Development of Mixed-Mode Chromatography with Mechanistic Modeling, Presented by Fritz D., Ypso-Facto SAS

POSTER SESSION B: Wednesday afternoon - Thursday

B01: Cost Reduction and Optimization of Perfusion Processes Through At-Line Measurement of Viability-Limiting Media Components, Presented by Jeremie B., 908 Devices

B02: Instant Implementation of Raman-Based PAT with Integrated Real-Time Process Control, Presented by Nick R., 908 Devices

B03: Quantification Challenges of Chromatin-Associated Host Cell DNA: An Underestimated Risk, Presented by Jørn H., ArcticZymes

B04: CGTC-HEK293: Advanced Suspension Cell Line for rAAV Therapy Manufacturing, Presented by Maria BG., Cell and Gene Therapy Catapult

B05: Novel Nanofiber-Based Microcarriers Designed for Improved Upstream Productivity of Viral Vector Biomanufacturing, Presented by Nils U., Cellevate AB

B06: Twin-Column Continuous Chromatography for Improving AAV Purification, Presented by Thomas MS., ChromaCon AG

B07: Sustainable Compendial Grade GMP Detergent Substitutes for Triton™ X-100 in Bioprocessing Applications, Presented by Nuria M., Croda International Plc

B08: UP.SIGHT 2nd Gen Enables a Validated and High Throughput Workflow for Developing Stable Producer Cell Lines with >99% Assurance of Clonality and High Clone Recovery, Presented by Lucia G., CYTENA GmbH

B09: ECOnti: Accelerated, Low Ecological Footprint, Manufacturing Platform for Continuous Production of Biotechnological Products, Presented by Natalia D., enGenes Biotech GmbH

B10: Phase-Separated Zwitterionic Polymeric Coacervates for the Isolation of Extracellular Vesicles, Presented by Jonathan G., ETH Zurich

B11: Enterprise MS Analytics Software Platform for Streamlined Development and Production of Emerging Therapeutic Modalities, Presented by Nino N., Genedata AG

B12: End-to-End Software Platform for Streamlined LC/MS-Based Multi-Attribute Method (MAM) Implementation, Presented by Albert VW., Genedata AG

B13: Intrinsic Dynamic Scanning Fluorimetry for Protein Stability Assessment, Presented by Michaela C., Ghent University

B14: Utilizing Protein A Membrane for Rapid Process Development in Cell Line Optimization, Presented by William B., W.L. Gore & Associates, Inc.

B15: Sponsor’s Options for Bioproduction Site: Advantages, Risks and Challenges, Presented by Ludivine D., Inits SMO

B16: Key Critical Reagents from Platform HCP ELISA Characterised for Their Suitability for GS Effex® HCP Testing, Presented by Guojie M., Lonza Biologics plc

B17: Scaling PAT with Swept Source Raman Sensor Network, Presented by Nili P., Massachusetts Institute of Technology

B18: Optimizing AAV Manufacturing in HEK293 Cells via Pathway Engineering, Presented by Rosalia CE., MeiraGTX UK II Ltd.

B19: Development of a Capture Resin to Support Process-Specific Host Cell Protein (HCP) Pattern Characterization, Presented by Valentino P., Menarini Biotech SRL

B20: A Multifaceted Strategy for Viral Safety and High Productivity in AAV Processes, Presented by Clothilde D., Merck & Cie

B21: Multi-Column Capture Processes - Constant Volume Approach for Continuous Process Scalability, Presented by Marco B., Merck Life Science S.L.

B22: Enabling Fully Continuous Inline Viral Inactivation, Presented by Thomas C., Millipore SAS (Merck)

B23: Achieve Higher AAV Productivity with the Next-Generation Transfection Reagent TransIT®-AAViator, Presented by Hayder AR., Mirus Bio LLC

B24: Crossing the Boundaries of AAV Production: Harnessing High Salt Concentrations to Improve Process Efficiency, Presented by Inigo D., Merck Life Sciences

B25: Addition of Trehalose During Harvesting Process Reduces Carry-Over of Host Cell-Derived Impurities, Presented by Kota H., Nagase

B26: Model-Based Optimization of the Anion Exchange Separation of Empty and Full Adeno-Associated Viral Capsids as Enabler for a Fast Design of MCSGP, Presented by Luca O., Politecnico Di Milano

B27: Clarifying the Process - Optimization of a Low-pI Fusion Protein Recovery and Impurity Removal Using 3M Harvest RC Chromatographic Clarifier, Presented by Ivo B., Polpharma Biologics

B28: End-to-End Advanced Continuous Bioprocess Automation, Presented by Wolfgang S., Qubicon AG

B29: Getting a Grip on Oxygen Transfer in Bioreactors: Automated kLa Determination Using the Software Lucullus®, Presented by Mohi A., SecureCell AG

B30: An Investigative Case Study of the Removal of Host Cell DNA from HEK Detergent Lysates Using 3M™ Harvest RC Chromatographic Clarifier, Presented by Ana M., Solventum

B31: Transforming all Tumor Sites: The Power of Systemic Enveloped Virotherapy, Presented by Lina S., StemVAC GmbH

B32: Process Raman for Monitoring and Control of Downstream Processes, Presented by Lin C., Thermo Fisher Scientific

B33: Enhancing Sustainability in Bioproduction Through Advances in DSP Technology, Presented by Carsten-Rene A., Tosoh Bioscience

B34: Design-of-Experiment (DoE) Approach Suggests Transfection Viable-Cell Density as Key Parameter for Optimized rAAV Productivity and Total DNA Amount for rAAV Packaging, Presented by Valerie L., Viralgen Vector Core

B35: Advances in Downstream PAT for Biologics, Vaccines and Gene Vectors, Presented by Dan S., Wyatt Technology

B36: High Performance Resin for Larger Biomolecules such as AAVs and pDNA, Presented by Julia B., YMC Europe GmbH

Additional Virtual Posters

V1: Agilent InfinityLab Online LC Solution for Real-Time Process Monitoring and Automation, Presented by Yang G., Agilent Technologies

V2: mRNA Purification Using Anion and Exchange Chromatography at Ambient Temperature, Presented by Luis G., Merck Life Science, S. L. U.

V3: Unveiling the Chromatic Secrets of a Therapeutic Protein - Root Cause Investigation of a Yellow Colored Protein, Presented by Philipp S., Novartis Pharmaceutical Manufacturing GmbH

V4: Efficient rAAV8 Capsid Quantification in Upstream Process Development with Two-Dimensional Liquid Chromatography, Presented by Simon S., Sartorius Stedim Biotech GmbH